如何使用字典用python修改字符串？

Question

我有一个字符串和一个字典。我必须用字典中的相应值替换字符串的部分（使用字典键）。

给定字符串： `

rna = AUGCAUGUACCGAAUGCUGAGGGGGCUUCCUAA

给定字典：

amino_acids = {"UUU" : "Phe", "UUC" : "Phe", "UUA" : "Leu", "UUG" : "Leu",
                "CUU" : "Leu", "CUC" : "Leu", "CUA" : "Leu", "CUG" : "Leu",
                "AUU" : "Ile", "AUC" : "Ile", "AUA" : "Ile", "AUG" : "Met",
                "GUU" : "Val", "GUC" : "Val", "GUA" : "Val", "GUG" : "Val",
                "UCU" : "Ser", "UCC" : "Ser", "UCA" : "Ser", "UCG" : "Ser",
                "CCU" : "Pro", "CCC" : "Pro", "CCA" : "Pro", "CCG" : "Pro",
                "ACU" : "Thr", "ACC" : "Thr", "ACA" : "Thr", "ACG" : "Thr",
                "GCU" : "Ala", "GCC" : "Ala", "GCA" : "Ala", "GCG" : "Ala",
                "UAU" : "Tyr", "UAC" : "Tyr", "UAA" : "STOP", "UAG" : "STOP",
                "CAU" : "His", "CAC" : "His", "CAA" : "Gln", "CAG" : "Gln",
                "AAU" : "Asn", "AAC" : "Asn", "AAA" : "Lys", "AAG" : "Lys",
                "GAU" : "Asp", "GAC" : "Asp", "GAA" : "Glu", "GAG" : "Glu",
                "UGU" : "Cys", "UGC" : "Cys", "UGA" : "STOP", "UGG" : "Trp",
                "CGU" : "Arg", "CGC" : "Arg", "CGA" : "Arg", "CGG" : "Arg",
                "AGU" : "Ser", "AGC" : "Ser", "AGA" : "Arg", "AGG" : "Arg",
                "GGU" : "Gly", "GGC" : "Gly", "GGA" : "Gly", "GGG" : "Gly"
                  }

预期输出：

Met-His-Val-Pro-Asn-Ala-Glu-Gly-Ala-Ser-*

问题： 我做错了什么？没有模块如何做到这一点？谢谢！

编辑：

解决方案

def rna_to_protein(rna):

    acids = [rna[i:i+3] for i in range(0, len(rna), 3)]

    protein ="-".join(amino_acids[acid] for acid in acids)
    protein = protein.replace("STOP", "*")

    return protein

Answer 1

您可以将rna字符串拆分为长度为 3 的单个字符串：

>>> rna = "AUGCAUGUACCGAAUGCUGAGGGGGCUUCCUAA"
>>> acids = [rna[i:i+3] for i in range(0, len(rna), 3)]
>>> acids
['AUG', 'CAU', 'GUA', 'CCG', 'AAU', 'GCU', 'GAG', 'GGG', 'GCU', 'UCC', 'UAA']

然后您可以使用它们在字典中查找酸：

>>> "-".join(amino_acids[acid] for acid in acids)
'Met-His-Val-Pro-Asn-Ala-Glu-Gly-Ala-Ser-STOP'